SCHEMBL29699406

SCHEMBL29699406

CCCCC(CC)Cc1cccc2c1nnn2C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.40
TLR8 Q9NR97 2/20 0.38
SLC9A1 P19634 5/20 0.35
KEAP1 Q14145 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP4Z1 Q86W10 4/20 0.33
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
XBP1 P17861 1/20 0.32
PPARG P37231 1/20 0.32
KMT2A Q03164 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
GLA P06280 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28573878 0.84 GRM2 (0.43) GRM2TLR8SLC9A1ALDH1A1KDM4E
SCHEMBL28885747 0.83 TLR8 (0.35) GRM2TLR8ALDH1A1KDM4EHPGD
SCHEMBL29007547 0.81 TLR8 (0.34) GRM2TLR8ALDH1A1KDM4EHPGD
SCHEMBL19018311 0.78 SLC9A1 (0.46) GRM2TLR8SLC9A1KEAP1ALDH1A1
SCHEMBL728570 0.78 ALDH1A1 (0.45) GRM2TLR8SLC9A1ALDH1A1KDM4E
SCHEMBL13586023 0.77 GRM2 (0.46) GRM2TLR8SLC9A1KEAP1PPARG
SCHEMBL19242816 0.75 GRM2 (0.44) GRM2TLR8SLC9A1KEAP1ALDH1A1
SCHEMBL28382191 0.75 ALDH1A1 (0.33) ALDH1A1KDM4ECA2CYP3A4TSHR
SCHEMBL21834057 0.73 GRM2 (0.43) GRM2TLR8SLC9A1ALDH1A1KDM4E
SCHEMBL2851554 0.73 ALDH1A1 (0.46) GRM2ALDH1A1KDM4ECA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252567-B2 Acrylate-based copolymer, method for producing said copolymer, friction reducer using said copolymer, and lubricating composition containing said friction reducer ADEKA CORPORATION (JP) 2025-03-18 US disclosed
EP-3981862-B1 ACRYLATE-BASED COPOLYMER, METHOD FOR PRODUCING SAID COPOLYMER, FRICTION INHIBITOR USING SAID COPOLYMER, AND LUBRICATING COMPOSITION CONTAINING SAID FRICTION INHIBITOR ADEKA CORP (JP) 2024-05-22 EP disclosed
WO-2024004763-A1 VISCOSITY INDEX IMPROVER COMPOSITION AND LUBRICATING OIL COMPOSITION 三洋化成工業株式会社 2024-01-04 WO disclosed
CN-113906070-B Acrylic acid ester copolymer, method for producing the same, friction inhibitor comprising the same, and lubricating oil composition containing the friction inhibitor 株式会社ADEKA 2023-10-24 CN disclosed
US-11760954-B2 Lubricant composition and lubricating oil composition containing said lubricant composition ADEKA CORPORATION (JP) 2023-09-19 US disclosed
CN-111433335-B Lubricant composition and lubricating oil composition containing the same 株式会社ADEKA 2023-05-02 CN disclosed
EP-3722398-B1 LUBRICANT COMPOSITION AND LUBRICATING OIL COMPOSITION CONTAINING SAME ADEKA CORP (JP) 2022-10-05 EP disclosed
US-20220251266-A1 ACRYLATE-BASED COPOLYMER, METHOD FOR PRODUCING SAID COPOLYMER, FRICTION REDUCER USING SAID COPOLYMER, AND LUBRICATING COMPOSITION CONTAINING SAID FRICTION REDUCER ADEKA CORPORATION (JP) 2022-08-11 US disclosed
EP-3981862-A1 ACRYLATE-BASED COPOLYMER, METHOD FOR PRODUCING SAID COPOLYMER, FRICTION INHIBITOR USING SAID COPOLYMER, AND LUBRICATING COMPOSITION CONTAINING SAID FRICTION INHIBITOR ADEKA CORPORATION (JP) 2022-04-13 EP disclosed