Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924036 | 1.00 | LMNA (0.35) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL29612241 | 0.95 | LMNA (0.35) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL23055660 | 0.84 | GABRA1 (0.42) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL12652906 | 0.81 | LMNA (0.35) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL29538054 | 0.77 | GABRA1 (0.45) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL467309 | 0.77 | GABRA1 (0.48) | LMNATRPA1SLC6A2HTR2BCHRM1 | |
| SCHEMBL6239179 | 0.76 | TSHR (0.46) | LMNASLC6A2HTR2BADRA1AGABRA1 | |
| SCHEMBL7626926 | 0.76 | CYP1A2 (0.39) | LMNACA1CA2CYP1A2TSHR | |
| SCHEMBL2593118 | 0.69 | GABRA1 (0.55) | LMNASLC6A2HTR2BGABRA1GABRB2 | |
| SCHEMBL22991520 | 0.68 | LMNA (0.47) | LMNATRPA1SLC6A2HTR2BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974725-A | Method for preparing pharmaceutical intermediate | 深圳市祥根生物医药有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-110586195-B | Chiral catalyst and preparation method and application thereof | 成都信立诺医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |