SCHEMBL29699504

SCHEMBL29699504

NS(=O)(=O)c1ccc(Nc2ccccc2)c([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 1.00
TDP1 Q9NUW8 2/20 1.00
POLB P06746 2/20 1.00
WNK1 Q9H4A3 1/20 0.69
DOT1L Q8TEK3 1/20 0.65
L3MBTL1 Q9Y468 3/20 0.62
ALDH1A1 P00352 2/20 0.59
HCAR3 P49019 1/20 0.59
MAPK1 P28482 1/20 0.59
CASP7 P55210 1/20 0.59
CA12 O43570 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
PKM P14618 2/20 0.54
CA1 P00915 1/20 0.54
ALDH3A1 P30838 2/20 0.53
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
KDM4E B2RXH2 1/20 0.53
VCAM1 P19320 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9487112 1.00 MAPT (1.00) MAPTTDP1POLBWNK1DOT1L
SCHEMBL10764508 0.87 MAPT (0.77) MAPTTDP1POLBWNK1DOT1L
SCHEMBL10761881 0.86 MAPT (0.76) MAPTTDP1POLBWNK1DOT1L
SCHEMBL11044743 0.85 MAPT (0.74) MAPTTDP1POLBWNK1DOT1L
SCHEMBL9817053 0.85 MAPT (0.74) MAPTTDP1POLBWNK1L3MBTL1
SCHEMBL9817060 0.85 MAPT (0.74) MAPTTDP1POLBWNK1DOT1L
SCHEMBL29363201 0.84 MAPT (0.72) MAPTTDP1POLBWNK1L3MBTL1
SCHEMBL7115658 0.84 MAPT (0.72) MAPTTDP1POLBWNK1L3MBTL1
SCHEMBL3821370 0.83 MAPT (0.71) MAPTTDP1POLBWNK1DOT1L
SCHEMBL16188270 0.83 ALDH3A1 (0.76) MAPTTDP1POLBWNK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3311994-B2 3D PRINTING METHOD FOR THE PRODUCTION OF A SPECTACLE LENS ZEISS CARL VISION INT GMBH (DE) 2026-04-29 EP disclosed
US-11921359-B2 Spectacle lens comprising at least one ultrathin lens and process for production thereof CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2024-03-05 US disclosed
EP-3488287-B1 PRINTING INK, PREFERABLY 3D PRINTING INK, SPECTACLE LENS, AND METHOD FOR MANUFACTURING AN EYEGLASS LENS ZEISS CARL VISION INT GMBH (DE) 2023-12-20 EP disclosed
US-11754860-B2 Photochromic lens with laminated film, method for producing a photochromic lens, and a spectacle frame CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2023-09-12 US disclosed
EP-3561579-B1 SPECTACLE LENS COMPRISING AT LEAST ONE ULTRATHIN PIECE OF GLASS AND METHOD FOR PRODUCING THE SAME ZEISS CARL VISION INT GMBH (DE) 2023-06-14 EP disclosed
CN-116219772-A Pretreatment liquid and image forming method 柯尼卡美能达株式会社 2023-06-06 CN disclosed
EP-3529658-B1 SPECTACLES LENS AND ITS PRODUCTION METHOD ZEISS CARL VISION INT GMBH (DE) 2022-11-30 EP disclosed
CN-110317496-B Aqueous inkjet composition 精工爱普生株式会社 2022-10-21 CN disclosed
US-11400668-B2 3D printing process for producing a spectacle lens CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2022-08-02 US disclosed
US-11384249-B2 Aqueous ink jet composition SEIKO EPSON CORPORATION (JP) 2022-07-12 US disclosed