Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363201 | 1.00 | MAPT (0.72) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL11209685 | 0.92 | MAPT (0.67) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL9906419 | 0.89 | FFAR4 (0.67) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL11515827 | 0.89 | MAPT (0.62) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL8029981 | 0.87 | MAPT (0.69) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL16188270 | 0.87 | ALDH3A1 (0.76) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL11694650 | 0.86 | ALDH3A1 (0.60) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL9487112 | 0.84 | MAPT (1.00) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL11044743 | 0.84 | MAPT (0.74) | MAPTTDP1POLBLMNAMEN1 | |
| SCHEMBL9817053 | 0.84 | MAPT (0.74) | MAPTTDP1POLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161577-A1 | FIRE RETARDANT AND SIMULTANEOUSLY DYEING METHOD FOR POLYESTER-BASED TEXTILE | 大京化学株式会社 | 2021-08-19 | — | — | WO | disclosed |
| US-10202339-B2 | Therapeutic compounds and compositions | AGIOS PHARMACEUTICALS, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-10202339-B2 | Therapeutic compounds and compositions | AGIOS PHARMACEUTICALS, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| EP-2992053-B1 | COLORING AGENTS NATURALISED WITH THE 6'-DEOXY-6'-(PIPERAZINYL)LACTOSE MOIETY | UNIV DEGLI STUDI DI FIRENZE (IT) | 2018-11-28 | — | — | EP | disclosed |
| EP-2992053-A1 | COLORING AGENTS NATURALISED WITH THE 6'-DEOXY-6'-(PIPERAZINYL)LACTOSE MOIETY | Universita' Degli Studi di Firenze (IT) | 2016-03-09 | — | — | EP | disclosed |
| US-20150299115-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC (US) | 2015-10-22 | — | — | US | disclosed |
| EP-2906212-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | Agios Pharmaceuticals, Inc. (US) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014177528-A1 | COLORING AGENTS NATURALISED WITH THE 6'-DEOXY-6'-(PIPERAZINYL)LACTOSE MOIETY | UNIVERSITA' DEGLI STUDI DI FIRENZE (IT) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014177528-A1 | COLORING AGENTS NATURALISED WITH THE 6'-DEOXY-6'-(PIPERAZINYL)LACTOSE MOIETY | UNIVERSITA' DEGLI STUDI DI FIRENZE (IT) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014062511-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2014-04-24 | — | — | WO | disclosed |
| EP-0124606-A4 | WATERLESS DIP DYE COMPOSITION AND METHOD OF USE THEREOF FOR TEXTILE-RELATED MATERIALS. | WILSON ROBERT B (US) | 1985-09-18 | — | — | EP | disclosed |
| EP-0126752-A4 | WATERLESS DIP DYE COMPOSITION AND METHOD OF USE THEREOF FOR SYNTHETIC ARTICLES. | WILSON ROBERT B (US) | 1985-09-16 | — | — | EP | disclosed |
| WO-1985003959-A1 | DYE COMPOSITION AND METHOD OF USE THEREOF FOR COLORING THERMOPLASTIC MATERIALS | BUCHANAN WILSON ROBERT | 1985-09-12 | — | — | WO | disclosed |
| EP-0126752-A1 | WATERLESS DIP DYE COMPOSITION AND METHOD OF USE THEREOF FOR SYNTHETIC ARTICLES | WILSON, Robert Buchanan (US) | 1984-12-05 | — | — | EP | disclosed |
| EP-0124606-A1 | WATERLESS DIP DYE COMPOSITION AND METHOD OF USE THEREOF FOR TEXTILE-RELATED MATERIALS | WILSON, Robert Buchanan (US) | 1984-11-14 | — | — | EP | disclosed |
| WO-1984001971-A1 | WATERLESS DIP DYE COMPOSITION AND METHOD OF USE THEREOF FOR SYNTHETIC ARTICLES | WILSON ROBERT B | 1984-05-24 | — | — | WO | disclosed |
| WO-1984001972-A1 | WATERLESS DIP DYE COMPOSITION AND METHOD OF USE THEREOF FOR TEXTILE-RELATED MATERIALS | WILSON ROBERT B | 1984-05-24 | — | — | WO | disclosed |
| US-4185962-A | Dyeing with organic dyestuffs dispersed in an organic liquid | SANDOZ LTD. (CH) | 1980-01-29 | — | — | US | disclosed |
| US-4009158-A | DYEING AND PRINTING FIBERS | SANDOZ LTD. (CH) | 1977-02-22 | — | — | US | disclosed |
| US-3865805-A | Azo compounds having a 2-nitro-4-phenylsulfamoyldiphenyl amine nucleus | ALTERMATT RUEDI | 1975-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202339-B2 | Therapeutic compounds and compositions | IDH3A, IDH1, IDH2 | MAPT 4036/4885TDP1 1344/4885POLB 3561/4885 |
| US-20150299115-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | IDH3A, IDH1, IDH2 | MAPT 4036/4885TDP1 1344/4885POLB 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.