Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669122 | 0.87 | HCAR2 (0.58) | HCAR2BCAT2MKNK1MKNK2BAZ2B | |
| Trifluoroacetic Acid SCHEMBL28310620 | 0.83 | HCAR2 (0.74) | HCAR2BCAT2KDM4EALDH1A1PLOD2 | |
| Trifluoroacetic Acid SCHEMBL29618256 | 0.76 | HCAR2 (0.50) | HCAR2BCAT2MKNK1MKNK2KDM4E | |
| Trifluoroacetic Acid SCHEMBL1786802 | 0.76 | CES1 (0.52) | HDAC6HDAC2HDAC8ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL27698110 | 0.76 | HCAR2 (0.50) | HCAR2BCAT2MKNK1MKNK2KDM4E | |
| SCHEMBL2871262 | 0.73 | HCAR2 (0.46) | HCAR2BCAT2HDAC6BRAFLCK | |
| SCHEMBL29883112 | 0.73 | HCAR2 (0.46) | HCAR2BCAT2MKNK1MKNK2BAZ2B | |
| SCHEMBL14865358 | 0.73 | HCAR2 (0.47) | HCAR2BCAT2CTSLHDAC6HDAC2 | |
| Trifluoroacetic Acid SCHEMBL30664883 | 0.73 | HDAC2 (0.52) | HDAC6HDAC2HDAC8HPGDTSHR | |
| Trifluoroacetic Acid SCHEMBL27505927 | 0.71 | HDAC6 (0.50) | HDAC6HDAC2HDAC8HDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820773-B2 | Tricyclic compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20220169650-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169650-A1 | TRICYCLIC COMPOUNDS | SLC10A1, PKD1, CEL | HCAR2 2053/4885BCAT2 1147/4885MKNK1 2508/4885 |
| US-11820773-B2 | Tricyclic compounds | SLC10A1, PKD1, CEL | HCAR2 2053/4885BCAT2 1147/4885MKNK1 2508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.