Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19877014 | 0.76 | NPC1 (0.46) | HCAR2POLB | |
| SCHEMBL2787762 | 0.76 | HCAR2 (0.38) | HCAR2BCAT2POLBCTSLITGAV | |
| SCHEMBL2787521 | 0.76 | HCAR2 (0.38) | HCAR2BCAT2POLBCTSLITGAV | |
| SCHEMBL2789018 | 0.76 | HCAR2 (0.38) | HCAR2BCAT2POLBCTSLITGAV | |
| SCHEMBL2790368 | 0.75 | HCAR2 (0.37) | HCAR2EGLN1BCAT2POLBCTSL | |
| SCHEMBL2871262 | 0.75 | HCAR2 (0.46) | HCAR2BCAT2KDM4EBRAFLCK | |
| SCHEMBL343830 | 0.75 | POLB (0.65) | POLBKDM4EMRGPRX4HDAC3HDAC1 | |
| SCHEMBL2789685 | 0.74 | HCAR2 (0.36) | HCAR2BCAT2POLBCTSLITGAV | |
| SCHEMBL2787729 | 0.73 | HCAR2 (0.35) | HCAR2BCAT2POLBCTSLITGAV | |
| Trifluoroacetic Acid SCHEMBL29699595 | 0.73 | HCAR2 (0.50) | HCAR2BCAT2KDM4ECTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |