Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182817 | 0.86 | TDP1 (1.00) | TDP1APPALOX5ALDH1A1MAPT | |
| SCHEMBL7277555 | 0.84 | CHRM1 (0.52) | TDP1CHRM1TAAR1ALDH1A1KMT2A | |
| SCHEMBL11038062 | 0.83 | ALDH1A1 (0.68) | TDP1CHRM1ALOX5ALDH1A1GAA | |
| SCHEMBL23694499 | 0.83 | CHRM1 (0.51) | TDP1CHRM1ALDH1A1GAADNM1 | |
| SCHEMBL9367557 | 0.83 | TDP1 (0.92) | TDP1APPALOX5ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28340928 | 0.82 | ALDH1A1 (0.70) | TDP1CHRM1ALDH1A1GAAKMT2A | |
| SCHEMBL10751278 | 0.82 | ALDH1A1 (0.66) | TDP1CHRM1ALOX5ALDH1A1GAA | |
| SCHEMBL3851800 | 0.81 | TDP1 (0.82) | TDP1APPALOX5ALDH1A1MAPT | |
| SCHEMBL27516564 | 0.81 | TDP1 (0.82) | TDP1APPALOX5ALDH1A1MAPT | |
| SCHEMBL16488388 | 0.81 | TDP1 (0.70) | TDP1APPALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220170904-A1 | SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |