Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SIGLEC9 | Q9Y336 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098110 | 1.00 | DDB1 (0.51) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL27863561 | 0.92 | ALDH1A1 (0.55) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL30279152 | 0.91 | KDM1A (0.52) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL25041437 | 0.91 | KDM1A (0.52) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL27494294 | 0.90 | ALDH1A1 (0.60) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL5241748 | 0.87 | ALDH1A1 (0.55) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| Hydrochloric Acid SCHEMBL1874442 | 0.86 | ALDH1A1 (0.53) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL25803083 | 0.84 | SIGLEC9 (0.51) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL27717981 | 0.84 | SIGLEC9 (0.54) | DDB1CRBNALDH1A1SIGLEC9POLB | |
| SCHEMBL29934005 | 0.82 | DDB1 (0.44) | DDB1CRBNALDH1A1SIGLEC9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779096-B | Fluorine-substituted cyclopropylamine compounds, and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-07-01 | — | — | CN | disclosed |