Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SIGLEC9 | Q9Y336 | 2/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29699681 | 0.82 | DDB1 (0.51) | DDB1CRBNALDH1A1GRM5POLB | |
| SCHEMBL1098110 | 0.82 | DDB1 (0.51) | DDB1CRBNALDH1A1GRM5POLB | |
| SCHEMBL27863561 | 0.79 | ALDH1A1 (0.55) | DDB1CRBNALDH1A1GRM5POLB | |
| SCHEMBL27494294 | 0.78 | ALDH1A1 (0.60) | DDB1CRBNALDH1A1GRM5POLB | |
| Hydrochloric Acid SCHEMBL21640127 | 0.76 | DDB1 (0.47) | DDB1CRBNALDH1A1GRM5POLB | |
| SCHEMBL19468965 | 0.76 | LATS1 (0.44) | LATS1 | |
| SCHEMBL29915272 | 0.76 | ALDH1A1 (0.42) | DDB1CRBNALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL25041437 | 0.75 | KDM1A (0.52) | DDB1CRBNALDH1A1GRM5POLB | |
| SCHEMBL30279152 | 0.75 | KDM1A (0.52) | DDB1CRBNALDH1A1GRM5POLB | |
| SCHEMBL5241748 | 0.75 | ALDH1A1 (0.55) | DDB1CRBNALDH1A1GRM5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |