Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700093 | 0.92 | MEN1 (0.67) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL29699847 | 0.91 | MEN1 (0.66) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL29699779 | 0.89 | MEN1 (0.64) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL29699739 | 0.89 | CYP3A4 (0.64) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL1899756 | 0.89 | MEN1 (1.00) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL29699842 | 0.86 | CYP3A4 (0.65) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL29699837 | 0.85 | MEN1 (0.58) | MEN1KMT2AAURKARPS6KB1POLB | |
| SCHEMBL1902344 | 0.83 | MEN1 (0.78) | MEN1KMT2AAURKARPS6KB1NPSR1 | |
| SCHEMBL1897273 | 0.82 | MEN1 (0.80) | MEN1KMT2AAURKARPS6KB1NPSR1 | |
| 4-Bromoaniline SCHEMBL7739202 | 0.81 | MEN1 (0.80) | MEN1KMT2AAURKARPS6KB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685371-A | Pyrazole carboxamide derivatives, their preparation and use | 四川大学 | 2022-07-01 | — | — | CN | disclosed |