SCHEMBL29700451

SCHEMBL29700451

O=Cc1ccc(-c2cccc(C=O)c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.67
TRIM33 Q9UPN9 1/20 0.67
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA9 Q16790 1/20 0.65
DRD1 P21728 2/20 0.56
ELANE P08246 1/20 0.53
ALDH1A1 P00352 3/20 0.50
CYP2A6 P11509 2/20 0.50
KIF11 P52732 1/20 0.47
CDK8 P49336 1/20 0.46
BRD4 O60885 1/20 0.46
UNG P13051 1/20 0.45
KCNH2 Q12809 1/20 0.44
IP6K1 Q92551 1/20 0.44
AXL P30530 1/20 0.42
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916092 1.00 TRIM24 (0.67) TRIM24TRIM33CA12CA1CA2
Hydrochloric Acid SCHEMBL7795298 0.98 TRIM24 (0.65) TRIM24TRIM33CA12CA1CA2
SCHEMBL11770226 0.95 TRIM24 (0.71) TRIM24TRIM33CA12CA1CA2
SCHEMBL27621710 0.93 TRIM24 (0.68) TRIM24TRIM33CA12CA1CA2
SCHEMBL1669178 0.91 DRD1 (0.59) TRIM24TRIM33CA12CA1CA2
SCHEMBL346974 0.91 TRIM24 (0.64) TRIM24TRIM33CA12CA1CA2
SCHEMBL29414645 0.88 TRIM24 (0.69) TRIM24TRIM33CA12CA1CA2
SCHEMBL97618 0.88 TRIM24 (0.69) TRIM24TRIM33CA12CA1CA2
SCHEMBL5711166 0.88 CYP2A6 (0.55) TRIM24TRIM33CA12CA1CA2
SCHEMBL20861897 0.88 TRIM24 (0.54) TRIM24TRIM33CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478970-B Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2023-11-03 CN claimed
CN-114478970-A Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2022-05-13 CN claimed
CN-114478970-B Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2023-11-03 CN disclosed
EP-4251313-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-10-04 EP disclosed
CN-116457084-A Improvements in or relating to organic compounds 奇华顿股份有限公司 2023-07-18 CN disclosed
WO-2022112204-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-06-02 WO disclosed
CN-114478970-A Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2022-05-13 CN disclosed