Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | DRD1 | P21728 | 4/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27796624 | 0.97 | DRD1 (0.53) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL1669178 | 0.92 | DRD1 (0.59) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL6032 | 0.92 | ALDH1A1 (0.68) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| Benzene SCHEMBL28288569 | 0.92 | ALDH1A1 (0.68) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL10969109 | 0.92 | ALDH1A1 (0.68) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL5733969 | 0.92 | ALDH1A1 (0.68) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL25288128 | 0.91 | CYP2A6 (0.58) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL1666706 | 0.91 | CYP2A6 (0.58) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL976904 | 0.91 | CYP2A6 (0.58) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 | |
| SCHEMBL27335985 | 0.91 | CYP2A6 (0.58) | CYP2A6ALDH1A1DRD1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011213-B | Multi-channel luminous fluorescent probe and preparation method and application thereof | 复旦大学 | 2020-05-12 | — | — | CN | claimed |
| CN-101268077-A | Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators | ASTRAZENECA AB (SE) | 2008-09-17 | — | — | CN | claimed |
| CN-107011213-B | Multi-channel luminous fluorescent probe and preparation method and application thereof | 复旦大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-105246866-B | The method of synthesis ingenol and its intermediate | 利奥实验室有限公司 | 2017-06-16 | — | — | CN | disclosed |
| CN-105246866-A | Methods of synthesis of ingenol and intermediates thereof | LEO LAB LTD | 2016-01-13 | — | — | CN | disclosed |
| CN-101535276-B | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC | 2013-08-28 | — | — | CN | disclosed |
| CN-101679447-A | pyrimidodiazepinone derivative | KYOWA HAKKO KIRIN CO LTD | 2010-03-24 | — | — | CN | disclosed |
| CN-101535276-A | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-09-16 | — | — | CN | disclosed |
| CN-101268077-A | Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators | ASTRAZENECA AB (SE) | 2008-09-17 | — | — | CN | disclosed |
| EP-0888290-B1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNAT UNIVERSITY (US) | 2006-12-27 | — | — | EP | disclosed |
| CN-1751047-A | Triazole compounds useful in therapy | PFIZER (US) | 2006-03-22 | — | — | CN | disclosed |
| CN-1474820-A | Benzodiazepine derivatives as GABA A receptor modulators | - | 2004-02-11 | — | — | CN | disclosed |
| CN-1446218-A | Benzimidazole derivatives, their preparation and their therapeutic use | SANOFI SYNTHELABO (FR) | 2003-10-01 | — | — | CN | disclosed |
| CN-1384835-A | Tricycle inhibitors of poly(ADP-ribose) polymerases | AGOURON PHARMA (US) | 2002-12-11 | — | — | CN | disclosed |
| US-6291702-B1 | AS AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICAL SPECIES AND FIND USE AS EFFICIENT ANTIOXIDANTS IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS. | FLORIDA INTERNATIONAL UNIVERSITY | 2001-09-18 | — | — | US | disclosed |
| US-6197825-B1 | EFFECTIVE AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICAL SPECIES AND FIND USE AS EFFICIENT ANTIOXIDANTS IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS. DIAMAGNETIC NITRONE COMPOUND (THE ?SPIN TRAP?) REACTS WITH A TRANSIENT FREE | FLORIDA INTERNATIONAL UNIVERSITY | 2001-03-06 | — | — | US | disclosed |
| US-6083988-A | AZULENYL NITRONES ARE EFFECTIVE AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICALS AND FIND USE AS EFFICIENT ANTIOXIDANT IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS | FLORIDA INTERNATIONAL UNIVERSITY | 2000-07-04 | — | — | US | disclosed |
| EP-0888290-A1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | Florida International University (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997019054-A9 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | — | 1997-08-07 | — | — | WO | disclosed |
| WO-1997019054-A1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNATIONAL UNIVERSITY (US) | 1997-05-29 | — | — | WO | disclosed |