Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31011018 | 0.92 | ACMSD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL10790137 | 0.92 | ACMSD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL300805 | 0.92 | ACMSD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL9403931 | 0.92 | ACMSD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL10790290 | 0.92 | ACMSD (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL11595517 | 0.91 | ACMSD (0.49) | ALDH1A1KDM4EHPGDHMGB1ACMSD | |
| SCHEMBL10790315 | 0.91 | ACMSD (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL29382599 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL30689750 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 | |
| SCHEMBL28034437 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251313-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2023-10-04 | — | — | EP | disclosed |
| WO-2022112204-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-06-02 | — | — | WO | disclosed |