⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyano-Pyrrolidine SCHEMBL3159964 | 0.96 | — | — | |
| SCHEMBL10274655 | 0.96 | — | — | |
| Cyano-Pyrrolidine SCHEMBL5076708 | 0.96 | — | — | |
| SCHEMBL311224 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL8584979 | 0.93 | CTSL (0.87) | — | |
| Hydrochloric Acid SCHEMBL28173618 | 0.93 | — | — | |
| SCHEMBL3428433 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL2579725 | 0.89 | — | — | |
| Ethane SCHEMBL28010291 | 0.86 | CTSK (0.87) | — | |
| Cyano-Pyrrolidine SCHEMBL17686049 | 0.85 | CTSL (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727939-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | claimed |
| WO-2024259116-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | claimed |
| CN-115141201-B | Cyano pyrrolidine-diaza-tetrastearane structural derivative and application thereof | 石家庄学院 | 2023-06-27 | — | — | CN | claimed |
| CN-115141201-A | Cyanopyrrolidine-diazatetrastane structural derivative and application thereof | 石家庄学院 | 2022-10-04 | — | — | CN | claimed |
| EP-3390391-B1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2022-09-14 | — | — | EP | claimed |
| EP-3433246-B1 | 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2022-05-04 | — | — | EP | claimed |
| CN-108290861-B | 1-cyano-pyrrolidine derivatives as USP30 inhibitors | 特殊治疗有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-107484415-B | 1-cyanopyrrolidine compounds as USP30 inhibitors | 特殊治疗有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-110092738-A | The preparation method of vildagliptin | 深圳市第二人民医院 | 2019-08-06 | — | — | CN | claimed |
| CN-109790169-A | With the Cyanopyrolidine derivatives as USP30 inhibitor activity | 特殊治疗有限公司 | 2019-05-21 | — | — | CN | claimed |
| JP-2002539243-A | — | — | 2002-11-19 | — | — | JP | claimed |
| US-20020165164-A1 | New effectors of dipeptidyl peptidase IV for topical use | DEMUTH HANS-ULRICH (DE) | 2002-11-07 | — | — | US | claimed |
| WO-2002083109-A1 | TREATMENT OF TYPE 2 DIABETES WITH INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING BV (NL) | 2002-10-24 | — | — | WO | claimed |
| CN-1370181-A | Effectors of dipeptidyl peptidase IV for topical use | PROBIODRUG GES FUR ARZNEIMITTE (DE) | 2002-09-18 | — | — | CN | claimed |
| EP-1206485-A2 | NEW EFFECTORS OF DIPEPTIDYL PEPTIDASE IV FOR TOPICAL USE | Probiodrug AG (DE) | 2002-05-22 | — | — | EP | claimed |
| EP-1162969-A2 | COMPOSITIONS FOR IMPROVING FERTILITY | Ferring BV (NL) | 2001-12-19 | — | — | EP | claimed |
| WO-2001077073-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2001-10-18 | — | — | WO | claimed |
| WO-2001014318-A2 | NEW EFFECTORS OF DIPEPTIDYL PEPTIDASE IV FOR TOPICAL USE | PROBIODRUG AG (DE) | 2001-03-01 | — | — | WO | claimed |
| WO-2000056296-A2 | COMPOSITIONS FOR IMPROVING FERTILITY | FERRING BV (NL) | 2000-09-28 | — | — | WO | claimed |
| US-4196287-A | Process for the catalytic production of 2-substituted pyridines | LONZA LTD. (CH) | 1980-04-01 | — | — | US | claimed |