SCHEMBL29700600

SCHEMBL29700600

CCc1nccn1Cc1ccc(-c2cc(CC(C)C)sc2S(=O)(=O)NC(=O)NCc2ccc(F)cc2)cc1F

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 18/20 0.50
MAS1 P04201 1/20 0.43
AGTR1 P30556 1/20 0.43
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23120789 1.00 AGTR2 (0.50) AGTR2MAS1AGTR1CYP3A4
Trifluoroacetic Acid SCHEMBL23120715 0.96 AGTR2 (0.47) AGTR2MAS1CYP3A4
SCHEMBL23121204 0.90 AGTR2 (0.54) AGTR2AGTR1CYP3A4
SCHEMBL29700607 0.90 AGTR2 (0.54) AGTR2AGTR1CYP3A4
SCHEMBL27081932 0.89 AGTR2 (0.54) AGTR2MAS1AGTR1CYP3A4
SCHEMBL25248583 0.88 AGTR2 (0.55) AGTR2CYP3A4
SCHEMBL29047252 0.88 AGTR2 (0.57) AGTR2AGTR1
SCHEMBL29700575 0.88 AGTR2 (0.52) AGTR2MAS1AGTR1CYP3A4
SCHEMBL23121148 0.88 AGTR2 (0.52) AGTR2MAS1AGTR1CYP3A4
SCHEMBL23120747 0.88 AGTR2 (0.50) AGTR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP claimed
US-12435072-B2 Compounds VICORE PHARMA AB (SE) 2025-10-07 US disclosed
US-20220388994-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2022-12-08 US disclosed
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388994-A1 NEW COMPOUNDS RXFP3, RXFP4, RXFP1 AGTR2 110/4885MAS1 538/4885AGTR1 62/4885
US-12435072-B2 Compounds RXFP3, RXFP4, ARG1 AGTR2 94/4885MAS1 657/4885AGTR1 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.