Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | THRB | P10828 | 1/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.81 |
| ▸ | HTR7 | P34969 | 3/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440302 | 0.90 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| SCHEMBL968283 | 0.90 | HSD17B10 (0.79) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| SCHEMBL329762 | 0.90 | HSD17B10 (1.00) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL18346074 | 0.88 | HSD17B10 (0.77) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL31670342 | 0.88 | HSD17B10 (0.97) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| SCHEMBL25189080 | 0.88 | HTR7 (0.81) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL6474417 | 0.88 | LMNA (0.64) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| SCHEMBL6782148 | 0.85 | LMNA (0.60) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| SCHEMBL4279959 | 0.84 | LMNA (0.67) | HSD17B10CYP1A2CYP2D6ALOX15TSHR | |
| SCHEMBL4286367 | 0.84 | LMNA (0.67) | HSD17B10CYP1A2CYP2D6ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772245-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20060199829-A1 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199829-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC2, HDAC11 | HSD17B10 285/4885CYP1A2 2392/4885CYP2D6 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.