Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 9/20 | 0.83 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.83 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.83 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | THPO | P40225 | 1/20 | 0.83 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151170 | 1.00 | PDE3B (0.83) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| SCHEMBL30151140 | 1.00 | PDE3B (0.83) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| SCHEMBL29701268 | 0.91 | PDE3B (0.83) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| Cilostazol SCHEMBL16128 | 0.91 | PDE3B (1.00) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| Cilostazol SCHEMBL1818013 | 0.91 | PDE3B (1.00) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| Cilostazol SCHEMBL29389547 | 0.91 | PDE3B (1.00) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| Cilostazol SCHEMBL5798390 | 0.90 | PDE3B (0.93) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| Cilostazol SCHEMBL5798394 | 0.89 | PDE3B (0.92) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| SCHEMBL28774449 | 0.89 | PDE3B (0.82) | PDE3BPDE3AMEN1ABCC4CACNA1F | |
| SCHEMBL7307973 | 0.88 | PDE3B (0.94) | PDE3BPDE3AMEN1ABCC4CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4151213-A1 | THERAPEUTIC AGENT FOR MILD COGNITIVE IMPAIRMENT | Shimadzu Corporation (JP) | 2023-03-22 | — | — | EP | claimed |
| CN-115551508-A | Therapeutic agent for mild cognitive impairment | 株式会社岛津制作所 | 2022-12-30 | — | — | CN | claimed |
| CN-119350296-A | Substituted quinolinone derivative and application thereof | 南京宁丹新药技术有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-114685449-B | Preparation and application of fluoro-substituted cilostazol derivative | 首都医科大学附属北京天坛医院 | 2024-12-24 | — | — | CN | disclosed |
| US-20230270737-A1 | Therapeutic Agent for Mild Cognitive Impairment | SHIMADZU CORPORATION (JP) | 2023-08-31 | — | — | US | disclosed |
| EP-4151213-A1 | THERAPEUTIC AGENT FOR MILD COGNITIVE IMPAIRMENT | Shimadzu Corporation (JP) | 2023-03-22 | — | — | EP | disclosed |
| CN-115551508-A | Therapeutic agent for mild cognitive impairment | 株式会社岛津制作所 | 2022-12-30 | — | — | CN | disclosed |
| CN-114685449-A | Preparation and application of fluorine-substituted cilostazol derivative | 首都医科大学附属北京天坛医院 | 2022-07-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270737-A1 | Therapeutic Agent for Mild Cognitive Impairment | CHAT, BDNF, FABP7 | PDE3B 341/4885PDE3A 303/4885MEN1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.