Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBASH3B | Q8TF42 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | F11 | P03951 | 3/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.40 |
| ▸ | IL1RN | P18510 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rebamipide SCHEMBL297016 | 0.90 | UBASH3B (0.72) | UBASH3BTACR1F11CCKBRERAP1 | |
| SCHEMBL296717 | 0.88 | UBASH3B (0.66) | UBASH3BTACR1F11CCKBRERAP1 | |
| SCHEMBL16666232 | 0.81 | UBASH3B (0.69) | UBASH3BTACR1F11CCKBRKDM4E | |
| SCHEMBL16666855 | 0.80 | UBASH3B (0.79) | UBASH3BTACR1F11CCKBRKDM4E | |
| SCHEMBL9293778 | 0.80 | UBASH3B (0.82) | UBASH3BTACR1F11CCKBRERAP2 | |
| SCHEMBL16666555 | 0.78 | UBASH3B (0.76) | UBASH3BTACR1F11CCKBRKDM4E | |
| SCHEMBL16666789 | 0.78 | UBASH3B (0.73) | UBASH3BTACR1F11KDM4EALDH1A1 | |
| Rebamipide SCHEMBL16667091 | 0.78 | UBASH3B (0.78) | UBASH3BTACR1F11CCKBRERAP1 | |
| Rebamipide SCHEMBL296716 | 0.78 | UBASH3B (0.78) | UBASH3BTACR1F11CCKBRERAP1 | |
| SCHEMBL16666431 | 0.77 | UBASH3B (0.75) | UBASH3BTACR1F11CCKBRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253619-B1 | Amine salt of carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-2253619-A1 | Amine salt of carbostyril derivative | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |