Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.39 |
| ▸ | BRD4 | O60885 | 6/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29702191 | 0.83 | BRD4 (0.47) | CREBBPBRD4SOS1ADORA2AADORA1 | |
| SCHEMBL29702363 | 0.82 | RAF1 (0.40) | RAF1BRAFCREBBPSOS1 | |
| SCHEMBL29702343 | 0.80 | BRD4 (0.43) | RAF1BRAFCREBBPBRD4ADORA2A | |
| SCHEMBL15344135 | 0.69 | TRPA1 (0.47) | CREBBPBRD4DYRK1A | |
| SCHEMBL3349243 | 0.68 | BRD4 (0.45) | CREBBPBRD4SOS1ADORA2AADORA1 | |
| SCHEMBL29702195 | 0.68 | BPTF (0.43) | BRD4 | |
| SCHEMBL29702339 | 0.67 | PIK3CD (0.45) | RAF1BRAFCREBBPBRD4 | |
| SCHEMBL6523541 | 0.65 | BRD4 (0.43) | CREBBPBRD4SOS1ADORA2AADORA1 | |
| SCHEMBL24924342 | 0.65 | BRD4 (0.40) | CREBBPBRD4SOS1ADORA2AADORA1 | |
| SCHEMBL1912411 | 0.64 | NSD2 (0.46) | CREBBPBRD4SOS1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621186-A | Heterocyclic compounds as modulators of RAS signaling pathway | 上海维申医药有限公司 | 2022-06-14 | — | — | CN | disclosed |