Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15931185 | 0.77 | KDM4E (0.39) | KDM4EKMT2AMEN1LMNAGAA | |
| SCHEMBL2184519 | 0.76 | SMN1; SMN2 (0.64) | KDM4EKMT2AMEN1LMNAGAA | |
| SCHEMBL14237207 | 0.75 | KDM4E (0.59) | KDM4EKMT2AMEN1LMNAGAA | |
| SCHEMBL31075741 | 0.74 | ALDH1A1 (0.48) | KDM4EKMT2AMEN1LMNAGAA | |
| SCHEMBL12045706 | 0.74 | ALDH1A1 (0.42) | KDM4EKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL30487489 | 0.74 | TDP1 (0.48) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL21314499 | 0.74 | TDP1 (0.48) | KDM4EKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL19283903 | 0.74 | LMNA (0.47) | KDM4EKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL2611076 | 0.73 | ALDH1A1 (0.47) | KDM4EKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL325226 | 0.72 | LMNA (0.46) | KDM4EKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167934-B | Cyclobutane-and azetidine-containing monocyclic and spiro compounds as alpha V integrin inhibitors | 百时美施贵宝公司 | 2022-06-10 | — | — | CN | disclosed |