Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29702191 | 0.83 | BRD4 (0.47) | LRRK2BRD4BRD9BRD7TAF1 | |
| SCHEMBL29702363 | 0.83 | RAF1 (0.40) | MCHR1PDE10APIK3CDPIK3CAPIK3CB | |
| SCHEMBL29702339 | 0.78 | PIK3CD (0.45) | LRRK2HPGDMCHR1PIK3CDPIK3CA | |
| SCHEMBL29702360 | 0.77 | LRRK2 (0.50) | LRRK2KDM4EALDH1A1GLAGAA | |
| SCHEMBL26100427 | 0.77 | LRRK2 (0.50) | LRRK2KDM4EALDH1A1GLAGAA | |
| SCHEMBL25213735 | 0.75 | LRRK2 (0.47) | LRRK2KDM4EALDH1A1GLAGAA | |
| SCHEMBL29380274 | 0.75 | LRRK2 (0.47) | LRRK2KDM4EALDH1A1GLAGAA | |
| SCHEMBL31083319 | 0.72 | LRRK2 (0.44) | LRRK2KDM4EALDH1A1GLAGAA | |
| SCHEMBL17076663 | 0.72 | LRRK2 (0.47) | LRRK2KDM4EALDH1A1GLAGAA | |
| SCHEMBL29702221 | 0.71 | LRRK2 (0.48) | LRRK2KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621186-A | Heterocyclic compounds as modulators of RAS signaling pathway | 上海维申医药有限公司 | 2022-06-14 | — | — | CN | disclosed |