Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522102 | 1.00 | PDE4B (0.39) | PDE4BKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29705167 | 0.87 | LMNA (0.44) | PDE4BKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL20520767 | 0.87 | LMNA (0.44) | PDE4BKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL20521434 | 0.80 | LMNA (0.41) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL20521025 | 0.79 | BAZ2B (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29705174 | 0.79 | BAZ2B (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29705211 | 0.78 | LMNA (0.50) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL20521839 | 0.78 | LMNA (0.50) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL20521007 | 0.77 | LMNA (0.39) | PDE4BKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29705126 | 0.77 | LMNA (0.39) | PDE4BKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |