Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521323 | 1.00 | LMNA (0.32) | LMNACASP1MEN1ABCC4PKM | |
| SCHEMBL23654372 | 0.81 | LMNA (0.36) | LMNACASP1MEN1ABCC4PKM | |
| SCHEMBL29705123 | 0.81 | KDM4E (0.35) | LMNAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20521561 | 0.81 | KDM4E (0.35) | LMNAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20521183 | 0.79 | KDM4E (0.35) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29705146 | 0.79 | KDM4E (0.35) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20520759 | 0.77 | GSK3B (0.31) | LMNACASP1KDM4EALDH1A1HPGD | |
| SCHEMBL29705203 | 0.77 | GSK3B (0.31) | LMNACASP1KDM4EALDH1A1HPGD | |
| SCHEMBL28735837 | 0.76 | LMNA (0.33) | LMNACASP1MEN1ABCC4PKM | |
| SCHEMBL25335713 | 0.73 | LMNA (0.30) | LMNACASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |