Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM4B | O94953 | 2/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050596 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2ADH1BADH1C | |
| SCHEMBL21355793 | 0.82 | ADH1B (0.37) | KDM4EALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL25299576 | 0.79 | KDM1A (0.44) | KDM4EALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL17338855 | 0.77 | ADH1B (0.34) | KDM4EALDH1A1SMN1; SMN2ADH1BADH1C | |
| SCHEMBL17847863 | 0.76 | KCNH2 (0.40) | KDM4EALDH1A1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL14855446 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL21355854 | 0.75 | NOS2 (0.53) | CYP2C9CCR5 | |
| SCHEMBL3475219 | 0.74 | SMN1; SMN2 (0.49) | KDM4EALDH1A1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL10647756 | 0.73 | ADH1B (0.37) | KDM4EADH1BADH1CADH1AADH7 | |
| SCHEMBL29837887 | 0.73 | ADH1B (0.38) | KDM4EALDH1A1SMN1; SMN2ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |