Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | ATR | Q13535 | 3/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215227 | 1.00 | ALDH1A1 (0.39) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL29705440 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL27215114 | 0.85 | CYP4F2 (0.41) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL26720570 | 0.85 | CYP4F2 (0.44) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL27215222 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL19464241 | 0.85 | LMNA (0.39) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL29705330 | 0.85 | CYP4F2 (0.41) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL29705852 | 0.85 | LMNA (0.39) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL29705287 | 0.81 | ALDH1A1 (0.37) | ALDH1A1POLBLMNACYP4F2CYP4A11 | |
| SCHEMBL29705486 | 0.81 | CYP4F2 (0.37) | ALDH1A1POLBLMNACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |