Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116895 | 1.00 | ATM (0.44) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL6583252 | 0.82 | CYP1A2 (0.45) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL31558555 | 0.82 | CYP1A2 (0.45) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL25341788 | 0.82 | ALDH1A1 (0.42) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL27215196 | 0.82 | TDP1 (0.47) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL15776706 | 0.82 | TDP1 (0.46) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL10058264 | 0.82 | ATM (0.39) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL27215211 | 0.81 | TDP1 (0.44) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL18681415 | 0.81 | TDP1 (0.44) | ATMTDP1ALDH1A1HIF1AVCAM1 | |
| SCHEMBL2975400 | 0.80 | ATM (0.40) | ATMTDP1ALDH1A1HIF1AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |