Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.61 |
| ▸ | CCR1 | P32246 | 3/20 | 0.61 |
| ▸ | CCR5 | P51681 | 3/20 | 0.61 |
| ▸ | CCR8 | P51685 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645103 | 1.00 | KDM4E (0.61) | KDM4ELMNAP4HTMCCR1CCR5 | |
| SCHEMBL30516908 | 1.00 | KDM4E (0.61) | KDM4ELMNAP4HTMCCR1CCR5 | |
| SCHEMBL1070654 | 0.83 | CCR1 (0.46) | KDM4ELMNAP4HTMCCR1CCR5 | |
| SCHEMBL30958843 | 0.83 | CCR1 (0.46) | KDM4ELMNAP4HTMCCR1CCR5 | |
| SCHEMBL24302699 | 0.80 | ALDH1A1 (0.52) | KDM4ELMNAP4HTMCCR1CCR5 | |
| Dipyridyl SCHEMBL27648895 | 0.79 | KDM4E (0.70) | KDM4ELMNAP4HTMCCR1CCR5 | |
| Dipyridyl SCHEMBL28330098 | 0.79 | KDM4E (0.70) | KDM4ELMNAP4HTMCCR1CCR5 | |
| SCHEMBL163378 | 0.79 | KDM4E (0.78) | KDM4ELMNAP4HTMCCR1CCR5 | |
| Dipyridyl SCHEMBL27651116 | 0.78 | KDM4E (0.88) | KDM4ELMNAP4HTMCCR1CCR5 | |
| Dipyridyl SCHEMBL29907716 | 0.78 | KDM4E (1.00) | KDM4ELMNAP4HTMCCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |