SCHEMBL163378

SCHEMBL163378

c1ccc(-c2cnc(-c3ccccn3)cn2)nc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.78
LMNA P02545 3/20 0.78
CCR1 P32246 3/20 0.78
CCR5 P51681 3/20 0.78
CCR8 P51685 3/20 0.78
P4HTM Q9NXG6 2/20 0.78
CYP1A2 P05177 1/20 0.78
POLB P06746 1/20 0.78
METAP1 P53582 1/20 0.78
BLM P54132 1/20 0.78
HIF1A Q16665 1/20 0.78
DOHH Q9BU89 1/20 0.78
NPC1 O15118 5/20 0.64
TP53 P04637 4/20 0.64
RAB9A P51151 4/20 0.64
ALOX15 P16050 3/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
HTT P42858 2/20 0.64
TDP1 Q9NUW8 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL30476148 0.91 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21338496 0.89 KDM4E (0.61) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
SCHEMBL23202420 0.87 KDM4E (0.58) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL9644480 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL4577373 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL1535115 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6555308-B1 Silver halide particles containing a polynuclear metal complex in which an organic compound is contained as a bridging ligand; high contrast, photosensitivity and good graininess; high speed forming a color image FUJI PHOTO FILM CO., LTD. (JP) 2003-04-29 US claimed
US-20250136629-A1 SELF-ASSEMBLED NANOPARTICLES FOR PHOTOTHERMAL THERAPY Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) 2025-05-01 US disclosed
EP-2630675-B1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD CAMBRIDGE DISPLAY TECH LTD (GB) 2019-09-11 EP disclosed
US-8926821-B2 Use of diazonium salts for the formation of thick layers on at least one surface of a substrate COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-01-06 US disclosed
CN-103097347-B Use of diazonium salts to form thick layers on at least one surface of a substrate COMMISSARIAT ENERGIE ATOMIQUE 2014-11-05 CN disclosed
US-20130239661-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2013-09-19 US disclosed
EP-2611773-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2013-07-10 EP disclosed
WO-2012029035-A1 USE OF DIAZONIUM SALTS FOR THE FORMATION OF THICK LAYERS ON AT LEAST ONE SURFACE OF A SUBSTRATE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-03-08 WO disclosed
US-6555308-B1 Silver halide particles containing a polynuclear metal complex in which an organic compound is contained as a bridging ligand; high contrast, photosensitivity and good graininess; high speed forming a color image FUJI PHOTO FILM CO., LTD. (JP) 2003-04-29 US disclosed
US-6537740-B1 High-speed color negative photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2003-03-25 US disclosed
US-6187928-B1 TREATING FUNGAL DISEASES THE ROCKEFELLER UNIVERSITY 2001-02-13 US disclosed
US-6087510-A Method of use of imidazolium cations THE ROCKEFELLER UNIVERSITY (US) 2000-07-11 US disclosed
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed
US-5874587-A FLUORESCENCE THE ROCKEFELLER UNIVERSITY (US) 1999-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136629-A1 SELF-ASSEMBLED NANOPARTICLES FOR PHOTOTHERMAL THERAPY TFRC, ALB, HSPA8 KDM4E 4353/4885LMNA 3734/4885CCR1 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.