Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215198 | 1.00 | NPC1 (0.33) | NPC1DGAT1MAPTF2RL1PNP | |
| SCHEMBL29705325 | 0.87 | DGAT1 (0.32) | NPC1DGAT1MAPTPNP | |
| SCHEMBL27215149 | 0.87 | DGAT1 (0.32) | NPC1DGAT1MAPTPNP | |
| SCHEMBL29705469 | 0.84 | DGAT1 (0.33) | NPC1DGAT1MAPTF2RL1 | |
| SCHEMBL19023260 | 0.84 | DGAT1 (0.33) | NPC1DGAT1MAPTF2RL1 | |
| SCHEMBL1565921 | 0.82 | DGAT1 (0.40) | DGAT1F2RL1 | |
| SCHEMBL18188139 | 0.82 | DGAT1 (0.33) | NPC1DGAT1F2RL1PNP | |
| SCHEMBL21818822 | 0.80 | ADORA3 (0.38) | NPC1DGAT1MAPTF2RL1 | |
| SCHEMBL1565412 | 0.80 | DGAT1 (0.32) | DGAT1F2RL1 | |
| SCHEMBL28453312 | 0.80 | NPC1 (0.37) | NPC1DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159745-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |