Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23163670 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM3MAOBPIM1 | |
| SCHEMBL19287158 | 0.83 | CHRM2 (0.45) | CHRM2CHRM1CHRM3MAOBPIM1 | |
| SCHEMBL514625 | 0.82 | MAOB (0.47) | MAOBPIM1PIM2MRGPRX4KIF11 | |
| SCHEMBL2091804 | 0.80 | CETP (0.44) | CHRM2CHRM1CHRM3MAOBDAO | |
| SCHEMBL29705676 | 0.79 | KDM4E (0.54) | MAOBPPARGMRGPRX4 | |
| SCHEMBL584635 | 0.79 | KDM4E (0.54) | MAOBPPARGMRGPRX4 | |
| SCHEMBL3147185 | 0.79 | GPR3 (0.50) | CHRM2CHRM1CHRM3PIM1PIM2 | |
| SCHEMBL30349245 | 0.79 | KDM4E (0.43) | CHRM2CHRM1CHRM3MAOBCETP | |
| SCHEMBL1035570 | 0.77 | CHRM2 (0.58) | CHRM2CHRM1CHRM3MAOBDAO | |
| SCHEMBL2097583 | 0.77 | CHRM5 (0.47) | CHRM2CHRM1CHRM3MAOBDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |