Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584635 | 1.00 | KDM4E (0.54) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL817396 | 0.83 | MAOB (0.52) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL30586063 | 0.82 | L3MBTL1 (0.57) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL2093115 | 0.80 | KDM4E (0.58) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL9797421 | 0.80 | L3MBTL1 (0.51) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL11515037 | 0.80 | MAOB (0.50) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL7762046 | 0.80 | L3MBTL1 (0.55) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL9811694 | 0.80 | L3MBTL1 (0.51) | KDM4EL3MBTL1POLBALDH1A1MAOB | |
| SCHEMBL23163670 | 0.79 | CHRM2 (0.47) | MAOBMRGPRX4PPARG | |
| SCHEMBL29705642 | 0.79 | CHRM2 (0.47) | MAOBMRGPRX4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |
| EP-4038052-A2 | PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS | Domain Therapeutics (FR) | 2022-08-10 | — | — | EP | disclosed |
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |