Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23164166 | 1.00 | MAOB (0.41) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL23164163 | 1.00 | MAOB (0.41) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL19384249 | 0.90 | KMT2A (0.46) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL19399867 | 0.82 | KDM4E (0.45) | MAOBHSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL23164157 | 0.80 | OGG1 (0.44) | MAOBALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL23164029 | 0.80 | PPARG (0.47) | MAOBALDH1A1LMNAMRGPRX4KMT2A | |
| SCHEMBL29705756 | 0.80 | PPARG (0.47) | MAOBALDH1A1LMNAMRGPRX4KMT2A | |
| SCHEMBL23164155 | 0.80 | OGG1 (0.44) | MAOBALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL23164031 | 0.80 | PPARG (0.47) | MAOBALDH1A1LMNAMRGPRX4KMT2A | |
| SCHEMBL28749488 | 0.80 | OGG1 (0.44) | MAOBALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |