Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23164029 | 1.00 | PPARG (0.47) | PPARGPPARASLC6A4HPGDMEN1 | |
| SCHEMBL23164031 | 1.00 | PPARG (0.47) | PPARGPPARASLC6A4HPGDMEN1 | |
| SCHEMBL28749488 | 0.80 | OGG1 (0.44) | SLC6A4KMT2AALDH1A1MAOBLMNA | |
| SCHEMBL29705667 | 0.80 | MAOB (0.41) | KMT2AMRGPRX4ALDH1A1MAOBLMNA | |
| SCHEMBL29705659 | 0.80 | OGG1 (0.44) | SLC6A4KMT2AALDH1A1MAOBLMNA | |
| SCHEMBL23164166 | 0.80 | MAOB (0.41) | KMT2AMRGPRX4ALDH1A1MAOBLMNA | |
| SCHEMBL23164155 | 0.80 | OGG1 (0.44) | SLC6A4KMT2AALDH1A1MAOBLMNA | |
| SCHEMBL23164157 | 0.80 | OGG1 (0.44) | SLC6A4KMT2AALDH1A1MAOBLMNA | |
| SCHEMBL23164163 | 0.80 | MAOB (0.41) | KMT2AMRGPRX4ALDH1A1MAOBLMNA | |
| SCHEMBL29705631 | 0.80 | OGG1 (0.44) | SLC6A4KMT2AALDH1A1MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |