Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428405 | 1.00 | MAOB (0.46) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL5352721 | 0.98 | MAOB (0.44) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL3901324 | 0.84 | LMNA (0.38) | MAOBCYP1A2GAAMAPTALDH1A1 | |
| SCHEMBL11138464 | 0.83 | MAOB (0.43) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL232409 | 0.82 | CA12 (0.45) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL3702205 | 0.80 | MAOB (0.44) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL4576483 | 0.80 | CA12 (0.44) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL8414445 | 0.78 | MAOB (0.46) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL1877066 | 0.78 | MAOB (0.42) | MAOBEGFRCYP1A2GAAMAPT | |
| SCHEMBL8171076 | 0.77 | NCEH1 (0.47) | CYP1A2MAPTALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |