Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705710 | 0.88 | DRD2 (0.41) | DRD2DRD3ALDH1A1POLBMEN1 | |
| SCHEMBL29705700 | 0.82 | SIRT2 (0.41) | FFAR1 | |
| SCHEMBL29705670 | 0.82 | ACACB (0.42) | ALDH1A1MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL29705548 | 0.81 | SIRT2 (0.42) | — | |
| SCHEMBL29705602 | 0.81 | SLC2A1 (0.40) | FFAR1 | |
| SCHEMBL29705686 | 0.80 | GRM5 (0.38) | ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL29428973 | 0.77 | AKR1C3 (0.42) | ALDH1A1POLBGAAHTTAKR1C3 | |
| SCHEMBL3859730 | 0.75 | AKR1C3 (0.54) | MAPTNOTUMFFAR1AKR1C3AKR1C1 | |
| SCHEMBL4618863 | 0.74 | KDM1A (0.43) | DRD2DRD3POLBFFAR1AKR1C3 | |
| SCHEMBL29705653 | 0.72 | FFAR1 (0.43) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |