Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29705602 | 0.94 | SLC2A1 (0.40) | FFAR1TP53SLC2A1RORCNR1H4 | |
| SCHEMBL29705739 | 0.89 | GRM5 (0.41) | GRM5FFAR1SLC2A1GRM4TRIM24 | |
| SCHEMBL29705700 | 0.88 | SIRT2 (0.41) | FFAR1NR1H4 | |
| SCHEMBL29705548 | 0.87 | SIRT2 (0.42) | — | |
| SCHEMBL29705630 | 0.80 | ACACB (0.41) | MCHR1RORC | |
| SCHEMBL29705691 | 0.80 | DRD2 (0.41) | FFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29705670 | 0.79 | ACACB (0.42) | FFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29705653 | 0.79 | FFAR1 (0.43) | FFAR1SLC2A1NR1H4 | |
| SCHEMBL29705719 | 0.77 | ADAM17 (0.43) | FFAR1SLC2A1 | |
| SCHEMBL28323610 | 0.75 | NR1H4 (0.58) | GRM5XDHCYP3A4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |