Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762825 | 1.00 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1NPC1RAB9A | |
| SCHEMBL17489126 | 0.83 | L3MBTL1 (0.59) | L3MBTL1SLC40A1GLO1SMN1; SMN2KDM4E | |
| SCHEMBL22313300 | 0.81 | L3MBTL1 (0.58) | L3MBTL1SLC40A1GLO1KDM4EPKM | |
| SCHEMBL12000989 | 0.79 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1KDM4EPKM | |
| SCHEMBL11060698 | 0.79 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1KDM4EPKM | |
| SCHEMBL10734794 | 0.79 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1KDM4EPKM | |
| SCHEMBL4518372 | 0.79 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1SMN1; SMN2KDM4E | |
| SCHEMBL2371864 | 0.79 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1KDM4EPKM | |
| SCHEMBL8688550 | 0.79 | L3MBTL1 (0.56) | L3MBTL1SLC40A1GLO1NPC1RAB9A | |
| SCHEMBL28295805 | 0.79 | L3MBTL1 (0.51) | L3MBTL1SLC40A1GLO1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993590-B2 | Pyranone compounds useful to modulate OMA1 protease | 712 NORTH INC. (US) | 2024-05-28 | — | — | US | claimed |
| EP-4399216-A1 | IMMUNOMODULATING AZALIDES | Zoetis Services LLC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023038852-A1 | IMMUNOMODULATING AZALIDES | ZOETIS SERVICES LLC (US) | 2023-03-16 | — | — | WO | disclosed |
| CN-111732548-B | N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof | 浙江大学 | 2022-06-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993590-B2 | Pyranone compounds useful to modulate OMA1 protease | OPA1, OLA1, PITRM1 | L3MBTL1 3927/4885SLC40A1 2353/4885GLO1 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.