Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CALCR | P30988 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706215 | 0.94 | F2 (0.45) | F2LNPEPANPEPOPRD1NTSR1 | |
| SCHEMBL29706391 | 0.86 | F2 (0.44) | F2LNPEPANPEPOPRD1NTSR1 | |
| SCHEMBL31256944 | 0.81 | LNPEP (0.55) | LNPEPANPEPNTSR1XIAPREN | |
| SCHEMBL29568610 | 0.78 | XIAP (0.47) | F2LNPEPANPEPNTSR1XIAP | |
| SCHEMBL22022378 | 0.77 | F2 (0.42) | F2CTSLCTSSCTSKNTSR1 | |
| SCHEMBL29721111 | 0.77 | XIAP (0.48) | LNPEPANPEPNTSR1XIAPREN | |
| SCHEMBL32677407 | 0.77 | XIAP (0.49) | F2LNPEPANPEPNTSR1XIAP | |
| SCHEMBL32677404 | 0.77 | XIAP (0.49) | F2LNPEPANPEPNTSR1XIAP | |
| SCHEMBL29649750 | 0.77 | XIAP (0.56) | LNPEPANPEPNTSR1XIAPREN | |
| SCHEMBL31124516 | 0.76 | F2 (0.46) | F2OPRD1NTSR1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615436-A | Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide | 中国医学科学院药物研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-114573686-A | Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof | 中国医学科学院药物研究所 | 2022-06-03 | — | — | CN | disclosed |