Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | CALCR | P30988 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706189 | 0.86 | F2 (0.47) | F2LNPEPANPEPOPRD1CALCR | |
| SCHEMBL29706215 | 0.86 | F2 (0.45) | F2LNPEPANPEPOPRD1CALCR | |
| SCHEMBL29706165 | 0.85 | XIAP (0.46) | — | |
| SCHEMBL2946630 | 0.84 | FAP (0.40) | F2OPRD1NTSR1 | |
| SCHEMBL30040454 | 0.79 | MDM4 (0.45) | — | |
| SCHEMBL29706417 | 0.78 | CASP3 (0.47) | — | |
| SCHEMBL31558763 | 0.76 | F2 (0.46) | F2LNPEPANPEPOPRD1REN | |
| SCHEMBL30445992 | 0.76 | CASP3 (0.39) | F2OPRD1NTSR1 | |
| SCHEMBL20888357 | 0.76 | REN (0.40) | OPRD1RENNTSR1 | |
| SCHEMBL30429968 | 0.75 | REN (0.46) | OPRD1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615436-A | Disulfide bond-containing polypeptide with serine protease activity inhibiting function, hybrid peptide derived from disulfide bond-containing polypeptide and application of disulfide bond-containing polypeptide | 中国医学科学院药物研究所 | 2023-08-18 | — | — | CN | disclosed |
| CN-114573686-A | Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof | 中国医学科学院药物研究所 | 2022-06-03 | — | — | CN | disclosed |