Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17878707 | 1.00 | ITGB3 (0.54) | ITGB3ITGA2BCTSKTACR1CTRB1 | |
| SCHEMBL10723335 | 0.92 | PRSS1 (0.61) | ITGB3ITGA2BCTSKTACR1CTSL | |
| SCHEMBL1841203 | 0.92 | PRSS1 (0.61) | ITGB3ITGA2BCTSKTACR1CTSL | |
| SCHEMBL13887440 | 0.92 | KYNU (0.60) | ITGB3ITGA2BCTSKTACR1CTSL | |
| SCHEMBL22029461 | 0.92 | KYNU (0.60) | ITGB3ITGA2BCTSKTACR1CTSL | |
| SCHEMBL1841202 | 0.92 | PRSS1 (0.61) | ITGB3ITGA2BCTSKTACR1CTSL | |
| SCHEMBL2597112 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BCTSKTACR1CTRB1 | |
| SCHEMBL14561115 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BCTSKTACR1CTRB1 | |
| SCHEMBL1023794 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BCTSKTACR1CTRB1 | |
| Hydrochloric Acid SCHEMBL28284500 | 0.90 | KYNU (0.59) | ITGB3ITGA2BCTSKTACR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233889-B1 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | SHANGHAI MICURX PHARMACEUTICAL CO LTD (CN) | 2022-07-06 | — | — | EP | disclosed |