Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011960 | 1.00 | NR3C2 (0.46) | NR3C2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5257024 | 0.87 | GAA (0.53) | NR3C2MMP12MAPTALDH1A1GAA | |
| SCHEMBL15797262 | 0.85 | MMP12 (0.48) | NR3C2MMP12MAPTALDH1A1GAA | |
| SCHEMBL34475158 | 0.82 | PARP1 (0.45) | NR3C2MMP12MAPTALDH1A1GAA | |
| SCHEMBL4179726 | 0.82 | ALDH1A1 (0.60) | NR3C2MMP12MAPTALDH1A1GAA | |
| SCHEMBL4049030 | 0.81 | MMP12 (0.54) | NR3C2MMP12MAPTALDH1A1PKM | |
| SCHEMBL30638088 | 0.78 | MMP12 (0.49) | NR3C2MMP12MAPTALDH1A1PKM | |
| SCHEMBL7868455 | 0.78 | MMP12 (0.49) | NR3C2MMP12MAPTALDH1A1PKM | |
| SCHEMBL23830531 | 0.78 | MMP12 (0.49) | NR3C2MMP12MAPTALDH1A1GAA | |
| SCHEMBL12060295 | 0.75 | TP53 (0.57) | NR3C2MMP12MAPTPKMPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114585616-A | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-06-03 | — | — | CN | disclosed |