Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | VDR | P11473 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707194 | 1.00 | CYP1A2 (0.50) | CYP1A2AGTR1LMNAKDM4EVDR | |
| SCHEMBL23041708 | 1.00 | CYP1A2 (0.50) | CYP1A2AGTR1LMNAKDM4EVDR | |
| SCHEMBL29707199 | 0.81 | HTR1A (0.43) | LMNAKDM4EMAPK1LIPEMAPT | |
| SCHEMBL23041328 | 0.81 | HTR1A (0.43) | LMNAKDM4EMAPK1LIPEMAPT | |
| SCHEMBL7775128 | 0.80 | CYP1A2 (0.65) | CYP1A2AGTR1LMNAKDM4EVDR | |
| SCHEMBL23041031 | 0.80 | LMNA (0.47) | CYP1A2LMNACYP2C19MAPK1LIPE | |
| SCHEMBL23041040 | 0.77 | MEN1 (0.43) | KDM4EMEN1KMT2AMAPK1LIPE | |
| SCHEMBL23041061 | 0.75 | TUBB1 (0.43) | LMNAMAPK1LIPESMPD1HDAC1 | |
| SCHEMBL29707204 | 0.75 | TUBB1 (0.43) | LMNAMAPK1LIPESMPD1HDAC1 | |
| SCHEMBL29707210 | 0.75 | BCHE (0.43) | MAPK1LIPEMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021510-A2 | CONJUGATES AND CONJUGATES FOR USE IN PREVENTING OR TREATING OF BRAIN DAMAGE AND NEURODEGENERATIVE DISEASES | Medicortex Finland Oy (FI) | 2022-07-06 | — | — | EP | disclosed |