Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554375 | 1.00 | MAPK1 (0.42) | MAPK1CDK7CLK4CDC7DAPK3 | |
| SCHEMBL29707258 | 0.80 | PIK3CD (0.41) | CDK7CLK4CDC7DAPK3MAP4K4 | |
| SCHEMBL29707230 | 0.75 | SMN1; SMN2 (0.38) | KMOKDM4EAAK1 | |
| SCHEMBL28554980 | 0.75 | SMN1; SMN2 (0.38) | KMOKDM4EAAK1 | |
| SCHEMBL28550503 | 0.71 | FLT3 (0.38) | CDK7CLK4CDC7DAPK3MAP4K4 | |
| SCHEMBL29707229 | 0.71 | FLT3 (0.38) | CDK7CLK4CDC7DAPK3MAP4K4 | |
| SCHEMBL28554374 | 0.71 | FLT3 (0.38) | CDK7CLK4CDC7DAPK3MAP4K4 | |
| SCHEMBL29707252 | 0.71 | FLT3 (0.38) | CDK7CLK4CDC7DAPK3MAP4K4 | |
| SCHEMBL17804189 | 0.69 | ABL1 (0.40) | CDK7CLK4KDM4EABL1PDGFRA | |
| SCHEMBL20662319 | 0.68 | MAPK1 (0.43) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574211-B | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |