Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | HCK | P08631 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707256 | 0.80 | MAPK1 (0.42) | ABL1DYRK1ACLK4CDK8CDC7 | |
| SCHEMBL28554375 | 0.80 | MAPK1 (0.42) | ABL1DYRK1ACLK4CDK8CDC7 | |
| SCHEMBL3194422 | 0.79 | PIK3C3 (0.51) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL29707230 | 0.77 | SMN1; SMN2 (0.38) | KMOAAK1ALDH1A1 | |
| SCHEMBL28554980 | 0.77 | SMN1; SMN2 (0.38) | KMOAAK1ALDH1A1 | |
| SCHEMBL14826051 | 0.74 | PIK3C3 (0.51) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL29790293 | 0.74 | — | — | |
| SCHEMBL21364619 | 0.73 | PIK3C3 (0.46) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL9380855 | 0.73 | PIK3C3 (0.48) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL3189520 | 0.72 | KDM4E (0.43) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574211-B | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |