Flortaucipir F 18

Flortaucipir F 18

SCHEMBL29707635

[18F]c1ccc(-c2ccc3c(c2)[nH]c2ccncc23)cn1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.77
ACHE P22303 3/20 0.56
KIF11 P52732 1/20 0.55
CHUK O15111 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flortaucipir F 18 SCHEMBL13640613 1.00 MAPT (0.77) MAPTACHEKIF11CHUK
Flortaucipir F 18 SCHEMBL29379518 1.00 MAPT (0.77) MAPTACHEKIF11CHUK
Flortaucipir SCHEMBL29439901 1.00 MAPT (0.77) MAPTACHEKIF11CHUK
Flortaucipir SCHEMBL14053964 1.00 MAPT (0.77) MAPTACHEKIF11CHUK
Flortaucipir SCHEMBL29773835 1.00 MAPT (0.77) MAPTACHEKIF11CHUK
Flortaucipir SCHEMBL29548430 1.00 MAPT (0.77) MAPTACHEKIF11CHUK
SCHEMBL21217176 0.87 MAPT (1.00) MAPTACHEKIF11
SCHEMBL17997396 0.84 MAPT (0.63) MAPTACHEKIF11
SCHEMBL20128568 0.84 MAPT (0.63) MAPTACHEKIF11CHUK
SCHEMBL22906721 0.83 MAPT (0.66) MAPTACHEKIF11CHUK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132190-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 ELI LILLY AND CO (US) 2026-05-14 US disclosed
US-20260125460-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 LILLY CO ELI (US) 2026-05-07 US disclosed
US-20250296997-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 ELI LILLY AND COMPANY 2025-09-25 US disclosed
US-20250064417-A1 REGIONAL TAU IMAGING FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE ELI LILLY AND COMPANY 2025-02-27 US disclosed
EP-4472679-A1 REGIONAL TAU IMAGING FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE Eli Lilly and Company (US) 2024-12-11 EP disclosed
US-20240309082-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 ELI LILLY AND COMPANY 2024-09-19 US disclosed
EP-4423128-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Eli Lilly and Company (US) 2024-09-04 EP disclosed
EP-4423127-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Eli Lilly and Company (US) 2024-09-04 EP disclosed
EP-4422751-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Eli Lilly and Company (US) 2024-09-04 EP disclosed
EP-4423129-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 Eli Lilly Company (US) 2024-09-04 EP disclosed
WO-2023076995-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 ELI LILLY AND COMPANY (US) 2023-05-04 WO disclosed
WO-2023076971-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 ELI LILLY COMPANY (US) 2023-05-04 WO disclosed
WO-2023077042-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 ELI LILLY AND COMPANY (US) 2023-05-04 WO disclosed
WO-2023070064-A1 O-GLCNACASE (OGA) INHIBITOR COMBINATION THERAPY ELI LILLY AND COMPANY (US) 2023-04-27 WO disclosed
WO-2023036936-A1 BIFUNCTIONAL MOLECULES AS PROTEASOME STIMULATORS FOR IMPROVED TARGETED PROTEIN DEGRADATION, AND THEIR USES AS TARGETED BOOSTING DEGRADERS (TARBODS) BOOSTER THERAPEUTICS GMBH (DE) 2023-03-16 WO disclosed
EP-4147723-A1 BIFUNCTIONAL MOLECULES AS PROTEASOME STIMULATORS FOR IMPROVED TARGETED PROTEIN DEGRADATION, AND THEIR USES AS TARGETED BOOSTING DEGRADERS (TARBODS) Booster Therapeutics GmbH (DE) 2023-03-15 EP disclosed
WO-2022251048-A1 ANTI-AMYLOID BETA ANTIBODIES AND USES THEREOF ELI LILLY AND COMPANY (US) 2022-12-01 WO disclosed
WO-2022192639-A2 ANTI-N3PGLU AMYLOID BETA ANTIBODIES AND USES THEREOF ELI LILLY AND COMPANY (US) 2022-09-15 WO disclosed
WO-2022192636-A1 ANTI-AMYLOID BETA ANTIBODIES AND USES THEREOF ELI LILLY AND COMPANY (US) 2022-09-15 WO disclosed
WO-2022150735-A1 ANTI-N3PGLU AMYLOID BETA ANTIBODIES AND USES THEREOF ELI LILLY AND COMPANY (US) 2022-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132190-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 IL36G, IL33, BACE1 MAPT 8/4885ACHE 1237/4885KIF11 3258/4885
US-20260125460-A1 COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34 IL36G, IL33, BACE1 MAPT 8/4885ACHE 1237/4885KIF11 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.