Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524941 | 1.00 | ADRB2 (0.45) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL16013596 | 0.90 | ADRB2 (0.44) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL5548218 | 0.88 | CCNC (0.45) | ADRB2NCF1GRM4GAKAAK1 | |
| SCHEMBL8909568 | 0.85 | ADRB2 (0.41) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL5018907 | 0.80 | ADRB2 (0.48) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL5275609 | 0.77 | NR4A2 (0.56) | — | |
| SCHEMBL24339331 | 0.75 | ADRB2 (0.49) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL30174521 | 0.75 | ADRB2 (0.49) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL1980284 | 0.74 | NR4A2 (0.56) | ADRB2NCF1GRM4PARP1GAK | |
| SCHEMBL9829215 | 0.74 | ADRB2 (0.51) | ADRB2NCF1GRM4PARP1GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4022058-A2 | COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS | Sixfold Bioscience Ltd. (GB) | 2022-07-06 | — | — | EP | disclosed |