Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16013596 | 0.92 | ADRB2 (0.44) | ADRB2NCF1SYKPARP1AAK1 | |
| SCHEMBL29707948 | 0.85 | ADRB2 (0.45) | ADRB2NCF1PARP1AAK1GAK | |
| SCHEMBL3524941 | 0.85 | ADRB2 (0.45) | ADRB2NCF1PARP1AAK1GAK | |
| SCHEMBL4367045 | 0.80 | FERMT2 (0.56) | FERMT2 | |
| SCHEMBL28529691 | 0.79 | ADRB2 (0.40) | ADRB2NCF1SYKPARP1AAK1 | |
| SCHEMBL8907641 | 0.76 | LOXL2 (0.49) | NCF1SYKFERMT2 | |
| SCHEMBL902310 | 0.76 | FERMT2 (0.56) | FERMT2 | |
| SCHEMBL15924893 | 0.75 | LOXL2 (0.47) | NCF1SYKFERMT2 | |
| SCHEMBL5018907 | 0.75 | ADRB2 (0.48) | ADRB2NCF1PARP1AAK1GAK | |
| SCHEMBL5548218 | 0.74 | CCNC (0.45) | ADRB2NCF1AAK1GAKGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048705-A1 | POTASSIUM CHANNEL BLOCKERS | UNIVERSITY COLLEGE LONDON (GB) | 1997-12-24 | — | — | WO | disclosed |