Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DHPS | P49366 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104612 | 1.00 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL2997564 | 0.92 | LIPE (0.49) | RAB9ANPC1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL15607795 | 0.89 | LIPE (0.61) | RAB9ANPC1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL13893964 | 0.89 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2LIPEL3MBTL1 | |
| SCHEMBL16333710 | 0.88 | LIPE (0.46) | RAB9ANPC1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL13765533 | 0.88 | LIPE (0.51) | RAB9ANPC1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL26109550 | 0.88 | POLB (0.50) | RAB9ANPC1MAPK1NR1H4PPARG | |
| SCHEMBL30586951 | 0.87 | MEN1 (0.51) | SMN1; SMN2LIPEALDH1A1MAPTMEN1 | |
| SCHEMBL124355 | 0.87 | MEN1 (0.51) | SMN1; SMN2LIPEALDH1A1MAPTMEN1 | |
| SCHEMBL2992272 | 0.87 | LIPE (0.51) | RAB9ANPC1SMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183652-A1 | DUAL CXCR4-BTK INHIBITORS | X4 PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| EP-4008328-A1 | PRIMARY CARBOXAMIDES AS BTK INHIBITORS | AbbVie Inc. (US) | 2022-06-08 | — | — | EP | disclosed |