SCHEMBL29709573

SCHEMBL29709573

CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.83

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 17/20 0.83
CCKAR P32238 2/20 0.72
IL23R Q5VWK5 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30816027 1.00 CCKBR (0.83) CCKBRCCKARIL23R
SCHEMBL29408672 1.00 CCKBR (0.83) CCKBRCCKARIL23R
SCHEMBL31236196 1.00 CCKBR (0.83) CCKBRCCKARIL23R
SCHEMBL29408680 0.99 CCKBR (0.82) CCKBRCCKAR
SCHEMBL31015828 0.98 CCKBR (0.82) CCKBRCCKARIL23R
SCHEMBL31378333 0.98 CCKBR (0.82) CCKBRCCKARIL23R
SCHEMBL30305897 0.98 CCKBR (0.83) CCKBRCCKARIL23R
SCHEMBL31015850 0.98 CCKBR (0.83) CCKBRCCKARIL23R
SCHEMBL31003974 0.96 CCKBR (0.80) CCKBRCCKARIL23R
SCHEMBL29362904 0.96 CCKBR (0.80) CCKBRCCKARIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3429599-B1 NANOPARTICLE TO TARGET CANCER UNIV GEORGETOWN (US) 2024-02-07 EP claimed
US-20240252696-A1 TARGETING THE CHOLECYSTOKININ-B RECEPTOR FOR IMAGING AND EARLY DETECTION OF PANCREATIC CANCER AND PRE-CANCEROUS LESIONS GEORGETOWN UNIVERSITY (US) 2024-08-01 US disclosed
EP-3429599-B1 NANOPARTICLE TO TARGET CANCER UNIV GEORGETOWN (US) 2024-02-07 EP disclosed
US-20230407265-A1 COMPOSITION AND METHODS FOR 3D CULTURE OF ISLET CELLS KANDEEL, FOUAD 2023-12-21 US disclosed
US-11696922-B2 Nanoparticle to target cancer GEORGETOWN UNIVERSITY (US) 2023-07-11 US disclosed
US-20220211738-A1 NANOPARTICLE TO TARGET CANCER GEORGETOWN UNIVERSITY (US) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211738-A1 NANOPARTICLE TO TARGET CANCER CCKBR, CCKAR, LNPEP CCKBR 1/4885CCKAR 2/4885IL23R 1079/4885
US-20240252696-A1 TARGETING THE CHOLECYSTOKININ-B RECEPTOR FOR IMAGING AND EARLY DETECTION OF PANCREATIC CANCER AND PRE-CANCEROUS LESIONS CCKBR, CCKAR, PROKR1 CCKBR 1/4885CCKAR 2/4885IL23R 416/4885
US-11696922-B2 Nanoparticle to target cancer CCKBR, CCKAR, LNPEP CCKBR 1/4885CCKAR 2/4885IL23R 1079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.