Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | QDPR | P09417 | 2/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.45 |
| ▸ | GRM5 | P41594 | 8/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.44 |
| ▸ | LIPC | P11150 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24793986 | 1.00 | NAMPT (0.51) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL24794715 | 0.92 | NAMPT (0.51) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL2946035 | 0.89 | NAMPT (0.51) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL27168139 | 0.88 | NAMPT (0.50) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL29656809 | 0.88 | NAMPT (0.50) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL29976423 | 0.88 | NAMPT (0.50) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL30778322 | 0.88 | NAMPT (0.50) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL520721 | 0.88 | QDPR (0.52) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL30957987 | 0.88 | QDPR (0.52) | NAMPTQDPRPDK4GRM1GRM5 | |
| SCHEMBL31129855 | 0.87 | NAMPT (0.51) | NAMPTQDPRPDK4GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761386-A | Substituted N-heterocyclic carboxamides as acid ceramidase inhibitors and their use as pharmaceuticals | 比亚尔R&D投资股份公司 | 2022-07-15 | — | — | CN | disclosed |